Table 1. Genes highly expressed (RPKM > 5) with RNA levels changed noticeable (fold >2 or fold <−2) and consistent in compound 331 treated U251 and C6 compared with the controls.
| Gene | Description | U251 |
C6 |
||
|---|---|---|---|---|---|
| Fold changes | p value | Fold changes | p value | ||
| DUSP1 | dual specificity phosphatase 1 | 2.77 | <1 × 10−13 | 2.74 | 6.61 × 10−13 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 2.507 | <1 × 10−13 | 5.18 | <1 × 10−13 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 2.467 | 1.31 × 10−12 | 2.95 | 5.14 × 10−13 |
| WSB1 | WD repeat and SOCS box containing 1 | 2.18 | 1.55 × 10−12 | 3.76 | <1 × 10−13 |
| RIOK3 | RIO kinase 3 | 2.04 | <1 × 10−13 | 2.06 | <1 × 10−13 |
| MCM3 | minichromosome maintenance complex component 3 | −2.32 | <1 × 10−13 | −2.23 | <1 × 10−13 |
| LMNB1 | lamin B1 | −2.68 | <1 × 10−13 | −2.50 | <1 × 10−13 |
| KIF20a | kinesin family member 20A | −2.72 | <1 × 10−13 | −2.13 | <1 × 10−13 |
| FAM64A | family with sequence similarity 64, member A | −2.74 | <1 × 10−13 | −3.14 | <1 × 10−13 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | −2.80 | <1 × 10−13 | −2.07 | <1 × 10−13 |
| PLK1 | polo-like kinase 1 | −2.81 | <1 × 10−13 | −3.94 | <1 × 10−13 |
| CDC20 | cell division cycle 20 | −3.45 | <1 × 10−13 | −3.41 | <1 × 10−13 |