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. 2015 Jul 8;15:213. doi: 10.1186/s12906-015-0751-z

Table 1.

Comparison of histopathological scores among the groups

Day Epithelialization
CON SSD Vaseline 5 % AJE 20 % AJE
2 0.0 ± 0.0 0.0 ± 0.0 0.3 ± 0.3 0. 00 ± 0.00 0.1 ± 0.1
14 1.5 ± 0.4 2.3 ± 0.07 2.9 ± 0.1** 2.9 ± 0.1*** 3.0 ± 0.0**
21 1.0 ± 0.0 2.7 ± 0.18*** 2.9 ± 0.1*** 2.9 ± 0.1*** 3.0 ± 0.0***
Vascularization
2 0.0 ± 0.0 0.0 ± 0.0# 1.6 ± 0.6* 1.8 ± 0.3* 1.6 ± 0.4*
14 1.2 ± 0.4 1.7 ± 0.4 1.9 ± 0.1 2.2 ± 0.2 2.2 ± 0.2
21 1.5 ± 0.2 1.7 ± 0.1 1.9 ± 0.2 2.3 ± 0.3 2.5 ± 0.1*
Granulation
2 0.0 ± 0.0 0.6 ± 0.1* 1.2 ± 0.0*** 1.5 ± 0.0*** 1.3 ± 0.1***
14 1.4 ± 0.2 1.9 ± 0.1 2.0 ± 0.1* 2.6 ± 0.1***,# 2.8 ± 0.2***,#
21 2.8 ± 0.0 2.8 ± 0.1 2.9 ± 0.1 2.9 ± 0.1 3.0 ± 0.1
Inflammation
2 2.6 ± 0.2 2.0 ± 0.1 2.9 ± 0.1 2.8 ± 0.2 2.7 ± 0.1
14 2.9 ± 0.1 2.3 ± 0.2 2.3 ± 0.1* 1.3 ± 0.2***,### 1.2 ± 0.1***, ##
21 2.3 ± 0.3 1.3 ± 0.1* 1.3 ± 0.1* 0.9 ± 0.1** 0.9 ± 0.3**
Collagen deposition
2 1.2 ± 0.1 1.1 ± 0.2 1.5 ± 0.1 1.3 ± 0.2 1.1 ± 0.2
14 2.2 ± 0.2 2.5 ± 0.2 2.7 ± 0.1 2.8 ± 0.1* 2.9 ± 0.1**
21 2.3 ± 0.2 2.6 ± 0.1 2.7 ± 0.2 2.9 ± 0.1* 3.0 ± 0.1*
Total score
2 1.0 ± 0.0 1.4 ± 0.1 1.2 ± 0.0 1.4 ± 0.1 1.5 ± 0.2
14 2.1 ± 0.1 2.5 ± 0.1 2.7 ± 0.1** 3.3 ± 0.2***, # 3.0 ± 0.1***
21 2.4 ± 0.0 3.2 ± 0.1** 3.3 ± 0.1*** 3.6 ± 0.1*** 3.9 ± 0.1***, # #

Abbreviations: CON control, SSD silver sulfadiazine, AJE Ampelopsis japonica tuberous root ethanol extract. Values are expressed as mean ± standard error of the mean (n = 3–8). * P < 0.05, ** P < 0.01, *** P < 0.001 vs. Control, # P < 0.05, ## P < 0.01, ### P < 0.001  vs. Vaseline