Table 4. Genes with European and American-specific effects 24 hours after infection.

Gene name (short name)	Population effect (fold-change)	Adjusted p-value	General expression change 1	Population expression change 2
European population
Cytochrome P450-4e3 (Cyp4e3)	0.72	0.0112	0	-
adenosine 3 (ade3)	0.75	0.0122	-	-
Cyp4d14	1.27	0.0325	-	0
American population
CG8834	0.67	<0.0001	+	0
timeless (tim)	1.47	<0.0001	-	-
CG17560	0.68	<0.0001	+	+
Niemann-Pick type C-1b (Npc1b)	0.69	<0.0001	-	-
CG11796	1.28	0.0001	+	+
CG31233	0.73	0.0003	0	-
CG13607	0.80	0.0014	0	0
CG2930	0.82	0.0025	+	0
Organic cation transporter 2 (Orct2)	0.76	0.0028	-	-
Starvation-upregulated protein (Sirup)	1.27	0.0029	-	0
CG3106	0.73	0.0033	-	-
CG15263	1.31	0.0076	0	0
CG5724	1.32	0.0150	+	+
Chorion factor 2 (Cf2)	0.78	0.0153	0	0
CG17752	0.77	0.0153	+	0
CG11892	0.77	0.0158	-	-
goliath (gol)	1.20	0.0173	-	-
CG8773	0.79	0.0293	0	-
Hemolectin (Hml)	0.79	0.0325	+	0
CG6770	1.23	0.0325	0	+
CG10657	0.79	0.0332	-	-
Ecdysone-induced protein 28/29kD (Eip71CD)	0.78	0.0334	-	-
CG42402	0.79	0.0395	0	0
slimfast (slif)	0.84	0.0480	+	0
CG4562	0.82	0.0480	-	-
Phosphatidylethanolamine-binding protein 1 (Pebp1)	0.77	0.0480	0	-
CG30431	0.86	0.0480	-	-
Cyp12d1-p	1.29	0.0480	-	0

¹ + or–symbols indicate significant over- or under-expression (p < 0.05) over all populations combined, 0 indicates no expression change (see also S1 Table)

² + or–symbols indicate significant over- or under-expression (p < 0.05) within the specific population (European or American), 0 indicates no expression change