Table 3.
Morbidity (measured by TBscore), 6-month all cause mortality and lost-to-follow up stratified by baseline results of LAM in HIV-infected (or test refused) patientsa
| All HIV-infected n/N (%) | LAM strip positive n/N (%) | LAM strip negative n/N (%) | P-value | |
|---|---|---|---|---|
| 6-month mortality (N = 393)b | 49/393 (13) | 9/32 (25) | 40/361 (11) | 0.021 |
| TB culture-positive only (N = 123)b | 6/17 (35) | 15/106 (14) | 0.032 | |
| Lost-to-follow up | 190/583 (33) | 38 (54) | 152 (30) | <0.001 |
| Culture-positive (N = 58) | 24/41 (59) | 34/140 (24) | <0.001 | |
| TBscore at enrolment | ||||
| Culture-positive (N = 181) | 6 (4-7.5) | 7 (6-8) | 5 (4-7) | 0.025 |
a14 HIV-infected and test refused patients with no reference standard result (see Fig. 1) excluded from the analyses of index test diagnostic accuracy are included in this analysis of morbidity and mortality. Thus a total of 583 patients are included in this table’s analysis
bOf the 583 HIV-infected patients with a LAM result, 190 were lost-to-follow-up at 6-months. Of the 393 patients with complete 6-month follow-up data, 123 were culture-positive TB