Table 3.
Multivariate analysis of overall survival and disease-free survival among male patients (N = 301)
| Overall survival | Disease-free survival | ||||
|---|---|---|---|---|---|
| Adjusted HR (95 % CI) | p value | Adjusted HR (95 % CI) | p value | ||
| Concurrent methylation | Present | 5.23 (2.45–11.17) | <0.001 | 3.66 (1.82–7.36) | <0.001 |
| Not present | 1 | 1 | |||
| Angiolymphatic invasion | Present | 4.41 (1.97–9.85) | <0.001 | 2.33 (1.30–4.18) | 0.005 |
| Not present | 1 | 1 | |||
| Age (continuous variable) | 1.032 (0.99–1.07) | 0.11 | |||
| Histology | MAC | 3.47 (0.97–12.41) | 0.056 | ||
| Non-MAC | 1 | ||||
| Perineural invasion | Present | 2.20 (1.26–3.85) | 0.006 | ||
| Not present | 1 | ||||
CI confidence interval, MAC mucinous adenocarcinoma