No. of participants
|
17,169 |
17,243 |
17,001 |
16,854 |
16,822 |
Age at cohort entry (mean ± SD), y |
63.1 ± 7.6 |
62.3 ± 7.7 |
61.7 ± 7.9 |
61.1 ± 8.0 |
60.2 ± 8.1 |
Ethnicity, %
|
|
|
|
|
|
African American |
13.7 |
15.7 |
19.1 |
22.2 |
32.6 |
Native Hawaiian |
5.8 |
6.4 |
7.0 |
7.0 |
6.5 |
Japanese American |
38.8 |
33.5 |
27.5 |
21.8 |
12.1 |
Latina |
17.6 |
20.9 |
23.6 |
25.6 |
25.1 |
White |
24.1 |
23.6 |
22.9 |
23.5 |
23.7 |
Family history of breast cancer, %
|
11.3 |
11.4 |
11.6 |
11.3 |
12.0 |
Education (>high school), %
|
52.0 |
51.5 |
50.4 |
49.3 |
46.8 |
BMI at cohort entry, %
|
|
|
|
|
|
<25 kg/m2
|
58.5 |
50.6 |
44.3 |
40.8 |
33.9 |
25–<30 kg/m2
|
29.1 |
32.0 |
33.8 |
34.1 |
33.4 |
≥30 kg/m2
|
12.4 |
17.4 |
21.9 |
25.1 |
32.7 |
Smoking status, %
|
|
|
|
|
|
|
|
|
|
|
|
Never |
61.5 |
59.4 |
56.6 |
53.6 |
45.9 |
Former |
29.4 |
29.9 |
30.6 |
30.5 |
31.6 |
Current |
9.1 |
10.7 |
12.8 |
15.9 |
22.6 |
Age at menarche, %
|
|
|
|
|
|
≤12 y |
45.7 |
47.8 |
48.2 |
49.3 |
50.9 |
13–14 y |
40.1 |
39.1 |
39.1 |
38.7 |
36.8 |
≥15 y |
14.2 |
13.1 |
12.7 |
12.0 |
12.3 |
Age at first live birth, %
|
|
|
|
|
|
No children |
14.1 |
12.4 |
12.2 |
11.7 |
12.2 |
≤20 y |
23.4 |
26.4 |
29.5 |
33.2 |
39.8 |
21–<31 y |
55.9 |
54.1 |
52.3 |
49.3 |
43.4 |
≥31 y |
6.6 |
7.0 |
6.1 |
5.8 |
4.7 |
Number of children for parous women, %
|
|
|
|
|
|
1 |
13.1 |
12.3 |
12.7 |
11.9 |
12.8 |
2–3 |
52.7 |
51.3 |
48.0 |
46.6 |
44.0 |
≥4 |
34.3 |
36.3 |
39.4 |
41.6 |
43.3 |
Age at and type of menopause, %
|
|
|
|
|
|
Natural |
|
|
|
|
|
<45 y |
9.3 |
9.6 |
9.9 |
10.6 |
11.9 |
45–<50 y |
19.3 |
19.5 |
19.8 |
20.2 |
19.9 |
50–<55 y |
27.9 |
27.6 |
26.4 |
24.6 |
21.3 |
≥55 y |
7.9 |
7.0 |
7.2 |
6.5 |
5.3 |
Oophorectomy |
|
|
|
|
|
<45 y |
9.8 |
10.0 |
10.4 |
10.5 |
12.5 |
45–<50 y |
5.0 |
5.3 |
5.1 |
5.0 |
4.9 |
≥50 y |
3.1 |
2.9 |
2.5 |
2.4 |
2.1 |
Hysterectomy |
|
|
|
|
|
<45 y |
13.0 |
13.5 |
14.3 |
15.4 |
17.6 |
45–<50 y |
3.4 |
3.4 |
3.1 |
3.6 |
3.3 |
≥50 y |
1.3 |
1.3 |
1.4 |
1.3 |
1.2 |
Use of hormone replacement therapy, %
|
|
|
|
|
|
No current or past estrogen use |
43.3 |
43.9 |
45.9 |
47.4 |
50.5 |
Past estrogen use with or without progesterone |
18.8 |
19.0 |
19.4 |
19.1 |
19.5 |
Current estrogen-only use |
17.0 |
16.4 |
15.9 |
15.8 |
14.8 |
Current estrogen use with past/current progesterone |
20.9 |
20.8 |
18.9 |
17.8 |
15.2 |
Energy intake, kcal/d |
1,770 ± 800 |
1,871 ± 876 |
1,952 ± 927 |
2,023 ± 995 |
2,073 ± 1,079 |
Alcohol use at least once a month in the past year, %
|
33.6 |
36.0 |
36.9 |
38.7 |
37.9 |