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. Author manuscript; available in PMC: 2016 Feb 26.
Published in final edited form as: Cell. 2015 Feb 26;160(5):928–939. doi: 10.1016/j.cell.2015.02.002

Figure 2. SML1 Deletion Rescues Mother Cell Lifespan of ETI Cells Independently of Telomere Length.

Figure 2

(A) SML1 deletion had no significant effect on the rate of bulk population senescence in ETI cells passaged on solid media to induce LTI-senescence. (B) Southern blot analysis of telomeric DNA restriction fragment lengths of cells taken from serial streaks shown in (A), using TG(1-3) repeat telomeric probe. ETI (tlc1Δ) and ETI sml1Δ(tlc1Δsml1Δ) displayed similar rates of telomere shortening and the lower end of the telomere length distributions were similar.

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