Fig 5. Geraniol action on vascular sprouting.

A-D: Phase-contrast microscopic images of rat aortic rings with vascular sprouting (borders marked by broken line) upon 6 days of treatment with vehicle (A), 100μM (B), 200μM (C) or 400μM geraniol (D). Scale bars: 700μm. E: Sprout area (mm²) of the outer aortic sprouting, as assessed by phase-contrast microscopy and computer-assisted image analysis. The aortic rings were exposed to vehicle (control; n = 8) or increasing concentrations of geraniol (100–400μM; n = 8) for 6 days. Means ± SEM. *P<0.05 vs. control.