Table 1. Microhemodynamic parameters of tumor microvessels.
Diameter (μm), VRBC (μm/s) and VQ (pL/s) of newly formed microvessels in CT26 tumors of vehicle-treated (control; n = 8) and geraniol-treated BALB/c mice (geraniol; n = 8), as assessed by intravital fluorescence microscopy and computer-assisted off-line analysis.
| d3 | d6 | d10 | d14 | |
|---|---|---|---|---|
| Diameter [μm] | ||||
| Control | 15.3 ± 0.6 | 12.4 ± 0.2 | 11.5 ± 0.2 | 11.4 ± 0.2 |
| Geraniol | 14.4 ± 0.5 | 12.8 ± 0.2 | 11.8 ± 0.2 | 11.7 ± 0.2 |
| V RBC [μm/s] | ||||
| Control | 126.9 ± 6.4 | 150.5 ± 7.6 | 166.4 ± 16.7 | 183.1 ± 20.6 |
| geraniol | 118.5 ± 8.4 | 131.6 ± 9.5 | 134.5 ± 12.3 | 133.9 ± 7.7* |
| VQ [pL/s] | ||||
| control | 18.4 ± 1.6 | 14.8 ± 0.9 | 14.1 ± 1.3 | 15.1 ± 1.5 |
| geraniol | 12.0 ± 0.7* | 12.3 ± 1.2 | 10.2 ± 1.1* | 10.7 ± 0.9* |
Means ± SEM.
*P<0.05 vs control.