Table 1.
Lung cancer: nuclear expression patterns [a–d] of lamins (positive samples/total number of tested samples)
| Tumour/method | Lamins A and C | Lamin B-type |
|---|---|---|
| Lung adenocarcinoma/IPO | 5/10 (a) | 3/10 (a) |
| 7/10 (c) | ||
| Lung squamous cell carcinoma/IPO | 8/13 (a) | 9/13 (a) |
| 1/13 (c) | 4/13 (c) | |
| Lung non-small cell carcinoma/IPO* | 0/3 (a) | 1/3 (a) |
| 1/3 (c) | 0/3 (c) | |
| 2/3 (d) | 2/3 (d) | |
| Lung small cell carcinoma/IPO | 1/15 (a) | 15/15 (a) |
| 7/15 (c) | ||
| Lung carcinoids/IPO | 2/6 (a) | 6/6 (a) |
| 2/6 (c) | ||
| Lung non-small cell carcinoma cell lines/IB | 4/4 (a) | 4/4 (a) |
| Lung small cell carcinoma cell lines/IB | 5/5 (c) | 5/5 (a) |
| Lung small cell carcinoma cell lines/IPO | 10/16 (c) | 16/16 (a) |
| 6/16 (d) | ||
| Lung adenocarcinoma cell lines/IPO | 3/4 (a) | 4/4 (a) |
| 1/4 (c) | ||
| Lung squamous cell carcinoma cell line/IPO | 1/1 (a) | 1/1 (a) |
| Lung large cell carcinoma cell line/IPO | 1/1 (a) | 1/1 (a) |
IPO – Immunoperoxidase, IB – Western/immunoblotting, (a) positive staining, (b) elevated staining/levels, (c) reduced staining/levels (d) no staining.
*
Lamin B1 only was evaluated.