Table 2.
Treatment | ||||
---|---|---|---|---|
H202 | + | + | + | + |
CHP | - | + | + | + |
Nrf2 siRNA | - | - | + | - |
SB203580 | - | - | - | + |
Gene | Fold change | |||
---|---|---|---|---|
GCLC | 1.2 ± 0.5 | 11 ± 1.2 | 0.8 ± 0.1 | 3.9 ± 0.4 |
GCLM | 1.2 ± 0.4 | 4.8 ± 0.3 | 1.0 ± 0.2 | 3.1 ± 0.4 |
Gpx | 0.9 ± 0.1 | 1.4 ± 0.1 | 0.7 ± 0.1 | 1.0 ± 0.3 |
GR | 1.5 ± 0.1 | 4.6 ± 0.3 | 0.9 ± 0.1 | 1.4 ± 0.2 |
GSTA-2 | 2.0 ± 0.3 | 2.5 ± 0.2 | 1.0 ± 0.2 | 2.1 ± 0.4 |
G6PDH | 1.1 ± 0.1 | 4.2 ± 0.4 | 0.9 ± 0.2 | 2.2 ± 0.2 |
NQ01 | 1.2 ± 0.4 | 3.1 ± 0.2 | 1.0 ± 0.3 | 1.9 ± 0.2 |
Trx-1 | 1.0 ± 0.2 | 1.5 ± 0.1 | 0.7 ± 0.2 | 1.0 ± 0.2 |
nNOS | 1.4 ± 0.1 | 0.5 ± 0.3 | 1.2 ± 0.1 | 1.4 ± 0.1 |
iMOS | 3.7 ± 0.1 | 1.9 ± 0.1 | 2.1 ± 0.2 | 2.8 ± 0.1 |