Figure 5.

Regression and final rejection of the allogeneic CT26 tumour in WT and Anx A5 KO mice. Allogeneic CT26 colorectal tumour cells were injected in the flank of Anx A5 KO or WT mice. At day 5, a measurable tumour was detectable and the consecutive allogeneic immune response against the tumour was monitored by measuring the tumour diameter with an electronic calliper at the indicated days after the injection. Note: WT mice showed a significant faster regression and final rejection of the tumour in comparison to Anx A5 KO animals. One out of three representative set of experiments is shown. KO: knock out; WT: wild type; **P < 0.01