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. 2015 Mar 24;6(11):8552–8566. doi: 10.18632/oncotarget.3298

Figure 2. Baseline characteristics of mitochondrial capacity of dermal fibroblasts of conplastic mouse strains.

Figure 2

A. Comparison of enzymatic activity of complex I in control and Nd2-mutant mice. The assay was performed in three independent experiments with isolated mitochondria of three different 12-month-old mice. ***p < 0.001. B. Comparisons of ATP levels in younger (3-month-old) and older (12-month-old) control and Nd2-mutant mouse fibroblasts. n = 5–9, *p < 0.05. C. ROS level determination of isolated fibroblasts of 3-month- and 12-month-old control and Nd2-mutant mice. n = 5–11, *p < 0.05. Data are given as mean ± SEM.