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. 2015 Apr 7;6(11):8676–8686. doi: 10.18632/oncotarget.3254

Figure 4. YAP and TAZ are functionally involved in miR-129-5p-mediated ovarian cancer cell proliferation and survival.

Figure 4

(A) miR-129-5p-induced suppression of TEAD transcriptional activity is reversed by expression of either YAP or TAZ in indicated cells. (B and C) Suppressive effects of miR-129-5p on ovarian cell proliferation (B) and survival (C) are antagonized by expression of YAP or TAZ. (D) TEAD transcriptional activity induced by antagomiR-129-5p is suppressed by depletion of either YAP or TAZ in indicated cells. (E and F) Promotion of ovarian cell proliferation (E) and survival (F) induced by antagomiR-129-5p is inhibited by YAP or TAZ silencing.