Figure 1. GANT61 and PI103 synergize to induce apoptosis in RMS cells.

RD, TE381.T, RMS13, RH30 and VJ cells were treated for 72 hours with indicated concentrations of PI103 and/or GANT61. Apoptosis was determined by DNA fragmentation of propidium iodide (PI)-stained nuclei using flow cytometry. Mean + S.D. of three independent experiments performed in triplicate are shown. Corresponding CI values are shown for all cell lines in Suppl. Table 1.