Figure 1. AGR2 expression in human head neck cancer.

(A) AGR2 DNA copy number from Peng's dataset and (B) mRNA expression from Ginos's dataset (as log2 median –centered ratio) for head neck cancer versus normal counterpart shown as raw data. (C) AGR2 DNA copy number of TCGA head neck cancer as shown as raw data. (D) Representative immunohistochemistry staining of AGR2 in oral mucosa as well as in HNSCC tissue with quantification in (E, One way ANOVA, P <0.001). Dys, dysplasia; SCC, squamous cell carcinoma; ***, P <0.001.