TABLE 2. Tumor latency for K5+/K19− and K5+/K19+ stem/progenitor cells with different combination.
Cell Line | Tumor Onset (Time first tumor appeared) | No. of mice that formed tumors (by 16 weeks) | No. of mice that formed tumors (by 16 weeks) |
---|---|---|---|
K5+/K19− mRas/mp53/wtErbB2 | 7 weeks | 10/10 | 10/10 |
K5+/K19+ mRas/mp53/wtErbB2 | 9 weeks | 8/10 | 10/10 |
K5+/K19− mRas/mp53/wtEGFR | 16 weeks | 2/7 | 7/7 |
K5+/K19+ mRas/mp53/wtEGFR | 7 weeks | 10/10 | 10/10 |