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Drug sensitivity was predicted for each case entering the MetaHNC-A dataset. Five therapeutic agents were investigated: A. Afatinib; B. Paclitaxel; C. Z-LLNle-CHO; D. Nutlin 3a; E. Rapamycin. Box-plots depict the predicted drug sensitivity in the six subtypes and the ROC curves estimate prediction accuracy of the more sensitive subtype against the others. p = Kruskal-Wallis test; AUC, area under the curve.
