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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Comput Neurosci. 2015 May 1;39(1):17–28. doi: 10.1007/s10827-015-0562-8

Figure 2.

Figure 2

Requirements from triggering phase 2 AD in the absence of phase 1 AD. Bottom traces show voltage recorded from the soma (red) and neuroma (blue) and top traces show corresponding activation of gNaP(A) For stimulation at 50 Hz, a total of four stimuli were needed to trigger AD originating in the soma. The same number of stimuli delivered at 40 Hz was unsuccessful, indicating that both the rate and number of evoked spikes are key. Notably, four spikes at 50 Hz is a weaker trigger than that provided by phase 1 AD spikes (cf. Fig 1). (B) Somatic AD required a more intense trigger when gNaP was reduced.