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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Thromb Haemost. 2015 Jun 11;13(7):1301–1309. doi: 10.1111/jth.13001

Fig. 1. Platelet FVIII expression in various 2bF8 mice with varying VWF phenotypes.

Fig. 1

The levels of platelet-FVIII activity (FVIII:C) were quantitated by a chromogenic assay on platelet lysates. Platelets were collected from eye bleeds, washed, and lysed in 0.5% CHAPS. Recombinant human B-domain deleted FVIII (rhF8) was used as the standard. Data are expressed as mean ± SD. The results demonstrate that the level of platelet-FVIII is significantly decreased in 2bF8 mice when platelets lack VWF.