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. 2015 Mar 10;6(12):10253–10266. doi: 10.18632/oncotarget.3520

Figure 6. Endothelial transfer of miR-503 elicit antitumor response during neoadjuvant chemotherapy.

Figure 6

Endothelial cells treated with chemotherapeutic agents release more exosomes that contain more miR-503. MiR-503 loaded exosomes induce a reduction of breast cancer cells proliferation and invasion caused by the inhibition of CCND2 and CCND3.