Table 4. IC50 values for doxorubicin and PKF 118-310.
Cell Line | IC50 of PKF (μM)a | IC50 of Dox (μg/ml)b | Combination Index | ||
---|---|---|---|---|---|
PKF | PKF+Dox | Dox | Dox+PKF | ||
HuH-7 | 0.6429 | 0.1964*** | 0.4287 | 0.1964** | 0.7662 |
HepG2 | 0.2231 | 0.08287** | 0.1677 | 0.08287** | 0.8657 |
SNU-449 | 2.704 | 0.4632** | 0.9750 | 0.4632** | 0.6458 |
SNU-387 | 1.525 | 0.2412** | 0.8539 | 0.2412** | 0.4430 |
IC50 PKF 118-310 concentration in two treatments for 48 h
IC50 of doxorubicin concentration in two treatments for 48 h
p < 0.01
p < 0.001.