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. 2015 Mar 14;6(12):10350–10365. doi: 10.18632/oncotarget.3585

Table 4. IC50 values for doxorubicin and PKF 118-310.

Cell Line IC50 of PKF (μM)a IC50 of Dox (μg/ml)b Combination Index
PKF PKF+Dox Dox Dox+PKF
HuH-7 0.6429 0.1964*** 0.4287 0.1964** 0.7662
HepG2 0.2231 0.08287** 0.1677 0.08287** 0.8657
SNU-449 2.704 0.4632** 0.9750 0.4632** 0.6458
SNU-387 1.525 0.2412** 0.8539 0.2412** 0.4430
a

IC50 PKF 118-310 concentration in two treatments for 48 h

b

IC50 of doxorubicin concentration in two treatments for 48 h

**

p < 0.01

***

p < 0.001.