Table 1. The effect of the ligands, Dp44mT, Bp4eT or PIH, or the chaotropic agent, guanidine hydrochloride (GndCl), on α-helix and β-sheet content of HSA.

	% α-Helix	% β-Sheets
HSA	67.73%	5.91%
HSA + Dp44mT	67.84%	5.89%
HSA + Bp4eT	66.86%	6.02%
HSA + PIH	67.17%	5.82%
HSA + GndCl*	1.79%	34.84%

^*Note: GndCl is used as a positive control to induce alterations in HSA secondary structure.