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. 2015 Mar 19;6(12):10498–10509. doi: 10.18632/oncotarget.3403

Figure 6. 5-FU promotes DKO HSC exhaustion.

Figure 6

(A) Survival curve. (B) Donor cell chimerism in recipients treated with DMSO (upper) or 5-FU (lower) at the indicated time points post-transplantation. Each bar represent one individual mice. (C) Peripheral WBC counts in recipients corresponding to those derived from control or DKO donor cells after treatment with DMSO control (left) or 125 mg/kg 5-FU (right) treatment at the indicated times post-transplantation. Data pooled from two experiments. n = 10, *p < 0.05.