Table 4. Univariate analysis of RT-PCR validated genes for predicting OS in: A) the cohort of patients with known CTCs count (N:43); B) the whole series of patients (N:70).
A | OS-initial series (N:43) | |||
---|---|---|---|---|
Hazard ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
ABCA13 | 1.40 (1.15 - 1.70) | 0.000673 | 1.60 (1.16 - 2.20) | 0.004 |
CEACAM | 1.47 (1.18 - 1.82) | 0.000556 | 1.73 (1.18 - 2.53) | 0.005 |
CRISP3 | 1.40 (1.16 - 1.68) | 0.000339 | 1.53 (1.15 - 2.03) | 0.003 |
MMP8 | 1.44 (1.19 - 1.74) | 0.000187 | 1.60 (1.18 - 2.17) | 0.002 |
MMP9 | 1.38 (1.15 - 1.65) | 0.000593 | 1.52 (1.15 - 2.00) | 0.003 |
OLFM4 | 1.46 (1.20 - 1.78) | 0.000167 | 1.64 (1.18 - 2.28) | 0.004 |
SELENBP1 | 1.21 (1.06 - 1.39) | 0.00501 | 1.44 (1.09 - 1.90) | 0.009 |
B | OS-global series (N:70) | |||
---|---|---|---|---|
Hazard ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
ABCA13 | 1.23 (1.08 - 1.41) | 0.00224 | 1.40 (1.13 - 1.81) | 0.00399 |
CEACAM | 1.26 (1.09 - 1.47) | 0.00232 | 1.49 (1.17 - 1.98) | 0.0027 |
CRISP3 | 1.18 (1.04 - 1.33) | 0.00771 | 1.29 (1.07 - 1.61) | 0.0138 |
MMP8 | 1.22 (1.09 - 1.37) | 0.000655 | 1.41 (1.16 - 1.77) | 0.00152 |
MMP9 | 1.34 (1.15 - 1.57) | 0.000151 | 1.47 (1.19 - 1.86) | 0.000644 |
OLFM4 | 1.26 (1.10 - 1.44) | 0.00102 | 1.38 (1.13 - 1.73) | 0.00278 |
SELENBP1 | 1.23 (1.09 - 1.39) | 0.000907 | 1.36 (1.14 - 1.69) | 0.00184 |