Table 5. Multivariable Cox models adjusted for CTCs (circulating tumor cells), SELENBP1+MMP9expression, PSA (prostatic specific antigen), AP (Alkaline phosphatase), LDH (Lactate dehydrogenase) and presence of visceral metastases.
| Patients with CTC count (N=43) | ||||
|---|---|---|---|---|
| HR | 95% CI | P-value | ||
| MMP9 - SELENBP1 | 14.53 | 1.91 | 110.75 | 0.0098 |
| Number of CTC (≥ or < 5) | 6.95 | 1.76 | 27.34 | 0.0056 |
| PSA | 0.99 | 0.99 | 1 | 0.7737 |
| FA | 1 | 1 | 1 | 0.02 |
| LDH | 0.99 | 0.99 | 1 | 0.3725 |
| Hb | 0.97 | 0.94 | 1 | 0.1001 |
| Visceral metastases | 2.89 | 0.45 | 18.63 | 0.2638 |
| All patients (N=70) | ||||
|---|---|---|---|---|
| HR | 95% CI | P-value | ||
| MMP9 - SELENBP1 | 3.42 | 1.11 | 10.52 | 0.0321 |
| PSA | 1 | 0.99 | 1 | 0.6633 |
| FA | 0.99 | 0.99 | 1 | 0.237 |
| LDH | 1 | 0.99 | 1 | 0.2737 |
| Hb | 0.96 | 0.93 | 0.99 | 0.0146 |
| Visceral metastases | 1.08 | 0.34 | 3.47 | 0.8901 |