Figure 5. Silencing Flot2 alone does not changed NPC cell motility.
(A) Efficiency of three siRNA sequences against Flot2 was evaluated by Quantitative real-time PCR. (B to D) CNE-1 cell motility was not affected by any of the three Flot2-silencing siRNAs. (B) Cell scattering and morphology. Scale bar = 50μm. (C) Wound-healing assay and (D) Transwell assay. (E) Flot2 silencing has no influence on the expression of EMT makers (E-cadherin, vimentin and β-catenin), TGF-β receptor 1 or total Src in CNE-1 cells. #P<0.01, +P<0.001.