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. 2015 Mar 26;6(12):9970–9984. doi: 10.18632/oncotarget.3667

Figure 1. Delphinidin sensitizes TRAIL-mediated apoptosis in human prostate cancer cells.

Figure 1

(A) The chemical structure of delphinidin. (B and C) Anti-proliferation effect of TRAIL in human prostate cancer cell lines. LNCaP (B) and Du145 cells (C) were treated with TRAIL in a dose- and time-dependent manner. LNCaP and Du145 cells were treated with different concentrations of TRAIL (0, 25, 50, 100, 150 ng/ml) for the indicated times (4, 8, 12 h) and cell viability was measured by MTT assay. The data are expressed as the mean ± SD for triplicates. (D) TRAIL induced apoptosis in prostate cancer cell lines. LNCaP and Du145 cells were treated with different concentration of TRAIL (0, 50, 100, 150 ng/ml) for 12 h. Cell viability was measured by a MTT assay.