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. 2015 May 25;112(21-22):375–386. doi: 10.3238/arztebl.2015.0375

Table. Psychotherapeutic interventions in children up to age 6.

Indication Intervention Age range Study design Effect Authors/year
A) 0–3 years
Problems relating to sleep, feeding, and behavior Psychodynamic mother–child therapy (PMCT)/ interactional guidance (IG); 6 sessions <30 months; average, 15 months RCT: comparison of two treatments, no untreated control group (n = 75) Improvement in sleep, feeding, and crying problems; improvement in maternal sensitivity (IG) and self-esteem(PMCT); effect strength not reported Robert-Tissot et al. 1996 [e46]
Functional problems in the regulation of feeding and sleep behavior “Watch, Wait, and Wonder” (WWW)/psychodynamic mother childt herapy(PMCT); ca. 10 sessions 10–30 months RCT (n = 67) Lessened severity of problems (assessed by mother), more secure bonding (WWW) Cohen et al.1999 [e49]
Post-partum depression (mother) Non-directive (NDT), cognitive behavioral (CBT), psychodynamic therapy (PMCT); ca. 10 sessions 25 months RCT: 3 treatment groups and 1 untreted control group (n = 193) Improvement of depression (PMCT) (transient, −2.6 EPDS points); alleviation of relationship problems with child Cooper et al. 2003 [e54]Muir et al. 1999 [e55]
Post-partum depression (mother) Mother–child therapyGroup interpersonal therapy; ca. 12 sessions 6–12 months RCT (n = 39) Improvement in depressive symptoms and parental stress; improved maternal attitude to child Clark et al. 2003 [e56]
Impaired mother–child relationship Psychoanalytic mother–child therapy;average, 29 sessions <18 months RCT (n = 80): one treated group, one TAU group Improved maternal depression (d = 0.39), maternal sensitivity (d = 0.42), and mother–child interaction (d = 0.58) Salomonsson et al. 2011 [36]
B) 4 – 6 years
Anxiety disorders Cognitive behavioral therapy 4–7 years RCT: 1 treatment group, 1 untreated group (n = 64) Significant improvement in symptoms of anxiety in the treated group Hirshfeld-Becker et al. 2010 [40]
Anxiety disorders Intervention based on parent group 3–5 years RCT: 1 treatment group, 1 untreated group (n = 146) Significant improvement in symptoms of anxiety (effect strength not reported) Rapee et al. 2010 [e57]
Post-traumatic stress disorder Trauma-oriented cognitive behavioral therapy 3–6 years RCT: 1 treatment group, 1 untreated group (n = 64) Significant improvement of PTSD symptoms (mean, from 7.6 to 2.9 symptoms per child) Scheeringa et al. 2011 [e58]
Depression Parent–child interaction therapy 3–7 years RCT: 1 treatment group, 1 control group with psychoeducation (n = 54); 25 dropouts Significant improvement in depression in both groups (effect of treatment on emotional perception and executive function, d= 0.11/0.83) Luby et al. 2012 [38]

RCT, randomized controlled trial; PTSD, post-traumatic stress disorder; TAU, treatment as usual