Figure 1.

The frequency of CD8⁺CD57⁺ T cells and short-term cardiovascular mortality in acute MI patients. The study population was divided into 48 cases of survival and seven cases of cardiovascular mortality, and the frequency of a specific T-cell population was compared between two patient groups. (a) Gating strategy. (b, c) The frequency of CD57⁺ cells (b) or CD28^null cells (c) among CD8⁺ T cells was compared between the two groups. (d, e) The frequency of CD57⁺ cells (d) or CD28^null cells (e) among CD4⁺ T cells was compared between the two groups. Data are expressed as the means±s.d. (f) Representative flow cytometry plots are presented for CD57 and CD28 expression in CD8⁺ T cells in patients who survived (left) and patients who suffered from cardiovascular mortality (right). (g) The patients (48 cases of survival and seven cases of cardiovascular mortality) were divided into two groups by median level (25%) of CD57⁺ T cell fraction in the CD8⁺ T-cell population. Kaplan-Meier plot shows that the 6-month survival rate was significantly lower in patients with CD8⁺CD57⁺ T cells ≥25% (dotted line) than in patients with CD8⁺CD57⁺ T cells <25% (solid line). *P<0.05. MI, myocardial infarction.