Table 2.
Genes related to quorum sensing in Vibrio cholerae and putative genes in Vibrio parahaemolyticus.
|
V. cholerae |
V. parahaemolyticus |
|||||
|---|---|---|---|---|---|---|
| Protein/Gen | Function | Reference | Accession number | Vibrio sp. | Protein identity | Gene identity |
| luxP | Detects the AI-2 as quorum sensing (QS) signal. | Miller et al. (2002) | CP006007.1 | V. parahaemolyticus O1:K33 | 65% | 67% |
| luxQ | Can be autophosphorylated, resulting in the transfer of a phosphate group to LuxO. | Raychaudhuri et al. (2006) | CP006005.1 | V. parahaemolyticus O1:Kuk | - | 64% |
| cqsA | Acts as an autoinducer to form biofilms. | Zhu and Mekalanos (2003) | BA000032.2 | V. parahaemolyticus RIMD 2210633 | 59% | 74% |
| luxO | Activates expression of four sRNAs that destabilize hapR mRNA repressing expression of HapR. | Jobling and Holmes (1997) | CP007004.1 | V. parahaemolyticus UCM-V493 | - | 75% |
| hapR | Master regulator of QS. | Jobling and Holmes (1997) | CP006008.1 | V. parahaemolyticus O1:K33 | 72% | 75% |
| aphA | Is a winged-helix transcription factor that controls virulence factor production in the closely related pathogen and QS. | Jobling and Holmes (1997), Skorupski and Taylor (1999) | CP007004.1 | V. parahaemolyticus UCM-V493 | 68% | |