. Author manuscript; available in PMC: 2015 Jul 9.

Published in final edited form as: Nature. 2015 Feb 18;519(7541):45–50. doi: 10.1038/nature14260

Extended Data Table 2.

Semi-quantitative measurements of β-endorphin immunoreactivity (see Extended Data Fig. 4a;

β-END in PVN	Total number	Total area	Mean area
VEHI	144±4.8	403.7±17.2	1838±121.4
90 min WIN (1 mg/kg BW)	170.8±4.4^***	497.6±15.1^***	2308±154.3
90 min ACEA (1 mg/kg BW)	177.3±3.9^***	477±8.4^**	2528±104.2
90 min ACEA (5 mg/kg BW)	144.2±5.7	407.9±17.9	1885±154.8

P<0.05,

^**

P<0.01,

^***

P<0.001 vs. VEHI).