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. 2015 Jul 8;83(8):3137–3145. doi: 10.1128/IAI.00230-15

TABLE 2.

Regulatory genes displaying at least a 2-fold (P < 0.05) change in transcript levels in both R. equi 103S and R. equi 103SP−/pVirRSvapA from those in the virulence plasmid-cured strain R. equi 103SP−

Gene name Annotation Expression in:
103S
 103SP−/pVirRSvapA
Fold changea P Fold changea P
REQ00140 TetR family transcriptional regulator 3.66 0.0001 2.11 0.0012
REQ00980 TetR family transcriptional regulator 2.97 0.0019 4.93 0.0007
REQ02910 MarR family transcriptional regulator −2.15 0.0044 −2.60 0.0004
REQ03830 IclR family transcriptional regulator −2.47 <0.0001 −2.52 <0.0001
REQ08990 IclR family transcriptional regulator −3.06 <0.0001 −2.87 0.0003
REQ10540 TCSb response regulator 2.58 0.0006 2.15 0.002
REQ13000 TetR family transcriptional regulator 2.68 0.0042 2.21 0.0072
REQ14460 Sigma 70 factor 24.20 <0.0001 15.61 0.0003
REQ15290 Transcriptional regulator 2.56 <0.0001 2.76 <0.0001
REQ15500 IclR family transcriptional regulator −2.65 0.0006 −2.91 0.0002
REQ15980 LuxR family transcriptional regulator 4.96 0.0001 4.78 0.0002
REQ21040 TetR family transcriptional regulator −2.42 0.0023 −2.60 0.0012
REQ23970 AraC family transcriptional regulator 2.96 0.0001 2.47 0.0008
REQ26080 RNA binding sensor regulator 2.05 0.0005 2.01 0.0001
REQ26260 MarR family transcriptional regulator 2.23 0.0016 3.57 0.0004
REQ31030 TCS response regulator KdpE 4.35 0.0002 4.29 0.0008
REQ31040 TCS sensor kinase KdpD 4.21 <0.0001 5.42 0.0002
REQ31260 AsnC family transcriptional regulator 2.26 0.0004 2.26 0.0009
REQ31580 Two-component system sensor kinase −2.45 0.0007 −2.13 0.0013
REQ33120 Two-component system sensor kinase 2.85 <0.0001 2.95 0.0001
REQ34960 Sigma 70 factor 5.00 <0.0001 4.95 <0.0001
REQ38490 NmrA family transcriptional regulator −7.68 <0.0001 −3.02 0.0019
REQ40160 PadR family transcriptional regulator −2.92 0.001 −2.27 0.005
REQ41890 GntR family transcriptional regulator −29.26 <0.0001 −22.74 <0.0001
REQ41960 IclR family transcriptional regulator −805.27 <0.0001 −926.06 <0.0001
REQ41970 ArsR family transcriptional regulator −176.15 <0.0001 −172.14 <0.0001
REQ42130 MarR family transcriptional regulator −2.60 0.0027 −2.05 0.0031
REQ44180 TetR family transcriptional regulator −3.16 <0.0001 −3.05 <0.0001
REQ45770 Purine catabolism regulatory protein −4.25 <0.0001 −3.96 <0.0001
REQ46220 Transcriptional regulator 5.72 0.0001 3.84 0.0043
REQ46610 PadR family transcriptional regulator −2.33 0.002 −2.42 0.0004
a

From expression in the virulence plasmid-cured strain R. equi 103SP−.

b

TCS, two-component system.