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Inhibition of host protein synthesis rescues chlamydial growth in moderately infected macrophages. RAW macrophages were treated with 0.5 μg/ml cycloheximide 4 h before or at the time of infection at various MOIs. IFU assays were performed at 24 h p.i. Black bars, untreated; white bars, cycloheximide addition at 4 h prior to infection; gray bars, cycloheximide addition at 0 h p.i. ****, P < 0.0001; ***, P < 0.001; *, P < 0.05. Shown are means and SD.
