TABLE 2.
Mean number of bacteria per cell in indicated cell types
| Cell type | Time (h) | Mean no. of bacteria of strain or species/cella |
||||||
|---|---|---|---|---|---|---|---|---|
|
F. tularensis |
Listeria monocytogenes | |||||||
| LVS | ΔiglA mutant | ΔiglC mutant | ΔiglG mutant | ΔiglI mutant | ΔpdpE mutant | |||
| J774 | 2 | 15 | 15.3 | 13.6 | 16.1 | 14.5 | 19.4 | 13.8 |
| 24 | 63.2* | 73.7*** | 95.8*** | 129.6*** | 97.8*** | 144.8*** | 335.8*** | |
| BMDM | 2 | 22.7 | 18.3 | 16.2 | 18.1 | 18.6 | 20.6 | 15.6 |
| 24 | 33.9 | 90.1*** | 56.0*** | 84.6*** | 99.5*** | 66.0*** | 155.5*** | |
| ASC−/− | 2 | 28.3 | 25.4 | 26.5 | 30.1 | 27.7 | 28.4 | 11.6 |
| 24 | 63.7*** | 128.7*** | 113.6*** | 119.3*** | 146.6*** | 153.8*** | 218.7*** | |
| MyD88−/− | 2 | 15.2 | 17.3 | 15.0 | 17.5 | 16.1 | 18.4 | 10.8 |
| 24 | 27.2 | 123.2*** | 93.0*** | 51.0** | 129.6*** | 78.2*** | 12.9 | |
| HeLa | 2 | 12.9 | 17.1 | 18.6 | 13.3 | 10 | 15.8 | 15.6 |
| 24 | 162.7*** | 135.5* | 302.5*** | 259.5*** | 237.7*** | 225.2*** | 199.4*** | |
a
Mean bacterial numbers of each strain at 2 h were compared to the mean numbers at 24 h, and the P values determined by the chi-square test or Fisher's exact test are indicated by asterisks (*, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001). Significant differences (P ≤ 0.05) between each of the F. tularensis mutants and LVS for the 24-h time point are indicated in bold.