Table 4. The odds ratios for developing new-onset DM, metabolic syndrome, dyslipidemia, or hypertension within the four-year period adjusting for age, gender, BMI, FPG, and HOMA-IR.

	DM		Metabolic syndrome		Dyslipidemia		Hypertension
	Odds ratio	p-value	Odds ratio	p-value	Odds ratio	p-value	Odds ratio	p-value
Ile	1.41 (1.12–1.76)	0.003	1.30 (1.09–1.55)	0.004	1.42 (1.22–1.64)	<.0001	1.01 (0.88–1.17)	0.838
Leu	1.52 (1.20–1.93)	0.001	1.34 (1.12–1.61)	0.002	1.38 (1.19–1.61)	<.0001	0.97 (0.83–1.12)	0.653
Val	1.24 (0.99–1.55)	0.056	1.13 (0.94–1.34)	0.191	1.21 (1.05–1.39)	0.007	0.94 (0.82–1.08)	0.388
Tyr	1.23 (1.01–1.49)	0.039	1.26 (1.08–1.47)	0.003	1.15 (1.02–1.29)	0.024	1.01 (0.89–1.14)	0.893
Phe	1.30 (1.09–1.55)	0.004	1.08 (0.93–1.24)	0.326	1.07 (0.95–1.20)	0.289	0.99 (0.88–1.12)	0.908
Ala	1.03 (0.84–1.25)	0.796	1.19 (1.02–1.38)	0.028	1.35 (1.20–1.51)	<.0001	1.05 (0.93–1.19)	0.395
Pro	1.09 (0.91–1.29)	0.333	1.10 (0.95–1.27)	0.199	1.13 (1.01–1.27)	0.026	0.98 (0.87–1.11)	0.798
Met	1.18 (0.98–1.41)	0.079	1.07 (0.92–1.23)	0.385	1.02 (0.91–1.15)	0.707	1.00 (0.89–1.13)	0.977
Ser	1.03 (0.85–1.25)	0.759	0.85 (0.72–0.99)	0.039	0.80 (0.72–0.90)	0.0001	0.93 (0.83–1.04)	0.197
Gly	1.03 (0.82–1.27)	0.805	0.83 (0.67–1.01)	0.071	0.85 (0.75–0.96)	0.009	0.95 (0.84–1.08)	0.464
PFAA index 1	1.31 (1.02–1.69)	0.036	1.59 (1.29–1.96)	<.0001	1.72 (1.47–2.02)	<.0001	1.07 (0.91–1.25)	0.397
PFAA index 2	1.39 (1.12–1.74)	0.003	1.36 (1.14–1.63)	0.001	1.47 (1.28–1.69)	<.0001	1.03 (0.90–1.19)	0.641

Values are odds ratios (95% confidence intervals) as a continuous variable per SD increment for developing metabolic syndrome, DM, dyslipidemia, or hypertension from logistic regressions. Significant odds ratios are highlighted in bold type.