Table 2.
Name in Review | Other Names | PDB Code/s (for PPIase Domain Containing Structures) | Proline Isomerase Activity? | Interacting Proteins in RNA Metabolism | Other Domains Present |
---|---|---|---|---|---|
FKBP4 | FKBP51 FKBP52 FKBP59 | 1Q1C (X-ray); 4DRJ (X-ray); 1QZ2 (X-ray); 4TW8 (X-ray); 1ROU (NMR); 1ROT (NMR); 1N1A (X-ray); 4LAY (X-ray); 4LAX (X-ray); 4LAW (X-ray); 4LAV (X-ray); 1P5Q (X-ray) | Yes | Hsp90, Ago2 | C-terminal TPR |
FKBP5 | FKBP51 FKBP54 | 3G6P (X-ray); 3G6Q (X-ray); 3G6R (X-ray); 3G6T (X-ray); 3G6U (X-ray); 1KT0 (X-ray); 1KT1 (X-ray); 4TW6 (X-ray); 4TXO (X-ray); 3O5D (X-ray); 3O5E (X-ray); 3O5G (X-ray); 3O5I (X-ray); 3O5J (X-ray); 3O5K (X-ray); 3O5L (X-ray); 3O5M (X-ray); 3O5O (X-ray); 3O5P (X-ray); 3O5Q (X-ray); 3O5R (X-ray); 4DRK (X-ray); 4DRM (X-ray); 4DRN (X-ray); 4DRO (X-ray); 4DRP (X-ray); 4DRQ (X-ray); 4JFI (X-ray); 4JFJ (X-ray); 4JFK (X-ray); 4JFL (X-ray); 4JFM (X-ray); 4TW7 (X-ray); 4W9O (X-ray); 4W9P (X-ray); 4W9Q (X-ray); 4DRH (X-ray); 4DRI (X-ray); | Yes | Hsp90, Ago2, Akt | C-terminal TPR |
FKBP6 | FKBP36 | 3B7X | No | Hsp90, Hsp27 | C-terminal TPR |
FKBP25 | FKBP3 | 3KZ7 (X-ray); 1PBK (X-ray); 4JYS (X-ray); 2KFV (NMR) | Yes | HDAC1, HDAC2, YY1, CK2, Nucleolin, HMG II | Extended N-terminus |