Table 2.

Antiviral drug doses recommended for prophylaxis according to the glomerular filtration rate, which is estimated based on creatinine clearance.

Drug	Creatinine clearance
		>60 mL/min	40–60 mL/min	25–40 mL/min	10–25 mL/min	<10 mL/min dialysis
Intravenous ganciclovir	5 mg/kg/day	2.5 mg/kg/day	1.25 mg/kg/day	1.5−1.25 mg/kg/day three times per week	1.5−1.25 mg/kg/day after dialysis
Oral valacyclovir*	2 g four times per day	2 g three times per day	1.5 g three times per day	1.5 g twice per day	1.5 g/day
Oral valganciclovir**	900 mg/day***	450 mg/day	450 mg 48/48 h	450 mg 2 times per week	not recommended****

^*1 tablet = 500 mg

^**1 tablet = 450 mg

^***certain authors recommend 450 mg/day ²

^****intravenous ganciclovir is recommended

Note: valacyclovir and valganciclovir should be given with meals