Table 3.
Drug | Creatinine clearance | ||||
---|---|---|---|---|---|
>60 mL/min | 40–60 mL/min | 25–40 mL/min | 10–25 mL/min | <10 mL/min dialysis | |
intravenous ganciclovir | 5 mg/kg twice per day | 2.5 mg/kg twice per day | 2.5 mg/kg/day | 1.25 mg/kg/day | 1.25 mg/kg after dialysis |
oral valganciclovir* | 900 mg twice per day | 450 mg twice per day | 450 mg/day | 450 mg every other day | not recommended** |
1 tablet = 450 mg
intravenous ganciclovir is recommended
Note: valacyclovir and valganciclovir should be given with meals