Figure 4.

Quantitative evaluation of P-selectin and ICAM-1 expression on rat mesenteric microvessels 24 h after intravenous injection of E. coli. SHAM, sham-operated rats; NT, non-treated rats; LR, lactated Ringer's solution (4 mL/kg)-treated rats; REP (4 mL/Kg LR + 50 mg/kg ethyl pyruvate)-treated rats. The presented values are the mean ± SEM for 3 samples/rat, with 3 rats/group. The analyses were performed using NIS-Elements BR software (Nikon). The results are presented as objectsx10³/μm². *p<0.001 versus SHAM, ^§p<0.01 versus SHAM and NT, ^†p<0.001 versus NT, ^?p<0.01 versus LR.