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. Author manuscript; available in PMC: 2015 Jul 9.
Published in final edited form as: J Neurochem. 2014 Jan 10;129(4):649–662. doi: 10.1111/jnc.12641

Fig. 4.

Fig. 4

α7 mediated inhibition of axon growth is dependent on a Gprin1 pathway. (a) An analysis of axon and GC morphology in cells treated with 10 µM PNU. Values are based on average percent change in axon growth from control cells (cells transfected with the same plasmid but treated with 0.1% DMSO). (b) An analysis of axon and GC morphology in cells treated with: PNU (10 µM); Ptx (1 µM), mastoparan (30 µM) Values are based on average change in axon growth from control cells which were treated with 0.1% DMSO alone. (c–d) Analysis of pGAP-43 and GTP-CDC42 expression within hippocampal neurons treated with PNU (10 µM), PNU+Bgtx (50 nM), or Control (0.1% DMSO) for 60 min in MP (c) and GCs (d). Immunofluoresecence signal in d represented as a heat map.