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. 2015 Mar 19;27(3):149–156. doi: 10.3109/08958378.2015.1013228

Table 6. Summary of urine BoE comparisons.

			LS means ± SE^a			Group comparison p value^b
Chemical constituent	Biomarker	Age (years)	SMK	MSC	NTC	SMK versus MSC	SMK versus NTC	MSC versus NTC
Nicotine	NicEq (µg mg⁻¹ CRE)^c	26–31	8.22 ± 1.27	7.92 ± 1.36	0.06 ± 1.27	1.0000	<0.0001	<0.0001
		32–37	8.03 ± 1.27	11.6 ± 1.42	0.04 ± 1.31	0.1908	<0.0001	<0.0001
		38–43	7.73 ± 1.27	10.49 ± 1.31	0.06 ± 1.27	0.3957	<0.0001	<0.0001
		44–49	9.53 ± 1.31	18.74 ± 1.86	0.04 ± 1.27	0.0003	<0.0001	<0.0001
NNK	NNAL-T (pg mg⁻¹ CRE)		656 ± 72.9	1594 ± 85.6	7.94 ± 72.9	<0.0001	<0.0001	<0.0001
Benzene	S-PMA (ng mg⁻¹ CRE)		2.63 ± 0.19	0.51 ± 0.23	0.46 ± 0.19	<0.0001	<0.0001	1.0000
Acrolein	3-HPMA (ng mg⁻¹ CRE)		1824 ± 73.7	160 ± 85.7	145 ± 74.3	<0.0001	<0.0001	1.0000
1-Hydroxypyrene	1-OHP-T (ng mg⁻¹ CRE)		0.22 ± 0.01	0.08 ± 0.02	0.05 ± 0.01	<0.0001	<0.0001	0.5439
1,3-Butadiene	MHBMA (ng mg⁻¹ CRE)		4.37 ± 0.29	0.45 ± 0.34	0.72 ± 0.29	<0.0001	<0.0001	1.0000
Crotonaldehyde	HMPMA (ng mg⁻¹ CRE)		7229 ± 263	598 ± 309	660 ± 263	<0.0001	<0.0001	0.8787
o-Toluidine	o-T (pg mg⁻¹ CRE)		193 ± 7.15	43.3 ± 8.84	41.2 ± 7.16	<0.0001	<0.0001	1.0000
2-Aminonaphthalene	2-AN (pg mg⁻¹ CRE)		31.2 ± 1.16	1.99 ± 1.44	1.23 ± 1.16	<0.0001	<0.0001	0.6813
4-Aminobiphenyl	4-ABP (pg mg⁻¹ CRE)		21.4 ± 0.93	2.74 ± 1.15	2.43 ± 0.93	<0.0001	<0.0001	0.8307
3-Aminobyphenyl	3-ABP (pg mg⁻¹ CRE)		11.1 ± 0.50	0.6 ± 0.62	0.66 ± 0.50	<0.0001	<0.0001	0.9412
Acrylamide	AAMA (ng mg⁻¹ CRE)		221 ± 8.65	106 ± 10.1	78.0 ± 8.73	<0.0001	<0.0001	0.1199
Acrylamide	GAMA (ng mg⁻¹ CRE)		35.1 ± 1.08	16.1 ± 1.26	15.8 ± 1.09	<0.0001	<0.0001	1.0000

^aLeast squares means ± SE.

^bBonferroni-adjusted. p values that exceeded 1.000 after adjustment are reported as 1.000.

^cSignificant group-by-age interaction (p < 0.05).