Table 3.
Factors associated with psychosocial problems at one-year follow-up
| Depression at T1 | Cognitive functioning at T1 | Fatigue at T1 | ||||
|---|---|---|---|---|---|---|
| N = 421 | N = 429 | N = 413 | ||||
| OR | (95 % CI) | OR | (95 % CI) | OR | (95 % CI) | |
| Baseline value of the problem | 10.39 | (4.65 - 23.22) | 4.21 | (2.56 - 6.93) | 3.53 | (2.20 - 5.64) |
| Ageing-related variables | ||||||
| Age: mean | 0.97 | (0.93 - 1.01) | 1.00 | (0.97 - 1.04) | 1.00 | (0.97 - 1.03) |
| Number of drugs: mean | 1.08 | (0.97 - 1.20) | 1.03 | (0.94 - 1.12) | 1.16 | (1.06 - 1.27) |
| Comorbidity: mean CCI score | 1.10 | (0.80 - 1.50) | 0.96 | (0.77 - 1.20) | 1.18 | (0.92 - 1.51) |
| Change in functional status | ||||||
| Not impaired | 1 | Reference | 1 | Reference | 1 | Reference |
| Was impaired | 2.56 | (0.69 - 9.54) | 1.42 | (0.62 - 3.25) | 1.41 | (0.67 - 2.94) |
| Became impaired | 3.99 | (1.14 - 13.90) | 1.91 | (0.86 - 4.24) | 2.14 | (1.04 - 4.43) |
| Persistently impaired | 7.78 | (2.60 - 23.29) | 2.34 | (1.21 - 4.54) | 1.17 | (0.65 - 2.11) |
| Socio-demographic variables | ||||||
| Gender (women) | 0.56 | (0.26 - 1.24) | 0.91 | (0.49 - 1.66) | 2.08 | (1.16 - 3.73) |
| Living conditions | ||||||
| With partner | 1 | Reference | 1 | Reference | 1 | Reference |
| With friends/family | 2.54 | (0.63 - 10.26) | 1.08 | (0.34 - 3.45) | 0.87 | (0.28 - 2.66) |
| Institutionalised | 2.02 | (0.30 - 13.69) | 0.28 | (0.03 - 2.86) | 0.63 | (0.09 - 4.20) |
| Alone | 2.70 | (1.31 - 5.56) | 1.10 | (0.61 - 1.97) | 0.97 | (0.55 - 1.71) |
| Age at leaving school | ||||||
| <15 years | 1 | Reference | 1 | Reference | 1 | Reference |
| 15 – 18 years | 0.91 | (0.41 - 2.02) | 1.18 | (0.62 - 2.26) | 1.95 | (1.06 - 3.61) |
| >18 years | 0.80 | (0.32 - 2.02) | 1.18 | (0.58 - 2.40) | 1.44 | (0.74 - 2.80) |
| Cancer-related variables | ||||||
| Cancer treatment | ||||||
| No cancer | 1 | Reference | 1 | Reference | 1 | Reference |
| Surgery only | 1.35 | (0.31 - 5.76) | 0.87 | (0.29 - 2.61) | 0.44 | (0.17 - 1.15) |
| Surgery and RT/HT therapy or both | 2.48 | (0.97 - 6.36) | 1.59 | (0.76 - 3.32) | 0.77 | (0.39 - 1.53) |
| Surgery and CT with or without any combination RT, HT, TT | 3.26 | (1.20 - 8.87) | 2.17 | (0.99 - 4.78) | 1.73 | (0.80 - 3.72) |
| Othera | / | 1.28 | (0.21 - 7.74) | 0.82 | (0.15 - 4.36) | |
| Percentage correctly classified | 86 % | 76 % | 71 % | |||
| Goodness-of-fit test | 0.90 | 0.18 | 0.30 | |||
OR, Odds Ratio; 95 % CI, 95 % Confidence Interval; CCI, Charlson Comorbidity Index; RT, radiotherapy; HT, hormonal therapy; CT, chemotherapy; TT, targeted therapy
aOther cancer treatments consisted of people who received no surgery but instead any of the following combinations: chemotherapy only (N = 2), chemo- and radiotherapy (N = 6), chemo- and targeted therapy (N = 1), hormonal therapy only (N = 2)