Table 2.

Multivariate analysis of factors associated with transplant outcomes

	HR	95 % CI	P value
Primary graft failure
DSA
MFI ≥ 10,000	1
2000 ≤ MFI < 10,000	0.940	0.284–3.177	0.919
MFI < 2000	0.187	0.048–0.730	0.016
OS
Disease status	2.839	1.702–4.736	0.000
Primary graft failure
GR	1
PGF	0.271	0.074–1.000	0.050
No primary graft failure	0.068	0.020–0.229	0.000
DFS
Disease status	3.593	2.212–5.836	0.000
PGF	3.125	1.564–6.244	0.000
GR	1
PGF	0.284	0.077–1.044	0.058
No primary graft failure	0.084	0.025–0.279	0.000
Relapse
Disease status	9.906	4.099–23.940	0.000
TRM
PGF
GR	1
PGF	0.209	0.056–0.790	0.021
No primary graft failure	0.031	0.0009–0.107	0.000
ANC
CD34	1.370	1.106–1.697	0.004
PLT
CD34	1.483	1.187–1.852	0.001
DSA
MFI ≥ 10,000	1
2000 ≤ MFI < 10,000	3.074	1.137–8.311	0.027
MFI < 2000	3.301	1.358–8.022	0.008

Abbreviations: HR hazard ratio, CI confidence interval, DSAs donor-specific antibodies, MFI median fluorescence intensity, OS overall survival, GR graft rejection, PGF poor graft function, DFS disease-free survival, TRM transplant-related mortality, ANC absolute neutrophil count, PLT platelet