Table 1.
Clinical findings in 61 infants with congenital and perinatal infection and specific IgM antibodies to Cytomegalovirus detected by enzymoimmunoassay
| Congenital | |||
| Patient No | Age (day/month) | IgM | Clinical and Laboratory data |
| 1 | 5 d | + | IUGR, cerebral calcifications. |
| 2 | 21 d | - | Ascites, renal problems, elevated liver enzymes. |
| 3 | 6 d | + | SGA, purpura, hepatosplenomegaly |
| 4, 8, 29 | 5 d, 5 d, 28 d | -, +, + | SGA |
| 5 | 18 d | + | Petechiae, hepatosplenomegaly, jaundice |
| 6, 14., 32 | 5 d, 8 d, 8 d | +, +, + | Hepatosplenomegaly, cerebral calcifications |
| 7 | 14 d | + | Sepsis, thrombocytopenia. |
| 9 | 20 m | - | AWGA, purpura, elevated liver enzymes. |
| 10 | 5 d | + | SGA, cerebral microcalcifications, microcephaly |
| 11 | 5 d | - | SGA, purpura, hepatosplenomegaly, thrombocytopenia |
| 12 | 4 d | - | AWGA, purpura, elevated liver enzymes, trombocytopenia. |
| 13 | 11 d | + | Sepsis, petechiae, thrombocytopenia |
| 15, 21, 33 | 5 d, 5 d, 5 d | -, +, - | SGA, purpura, HIV+. |
| 16 | 6 d | - | Cerebral calcifications, thrombocytopenia, HIV+ mother. |
| 17 | 5 d | + | Foetal dystrophy, inclusion-bearing cells in urine. |
| 18 | 14 d | S/s | IUGR, sepsis, foetal dystrophy |
| 19 | 8 d | + | Hepatosplenomegaly, sepsis, died of hepatic failure |
| 20 | 18 d | + | SGA, hydrocephalus, respiratory problems |
| 22 | 3 m | S/s | Cerebral calcifications, congenital toxoplasmosis |
| 23 | 24 d | - | Cholestasis, purpura, cerebral calcifications, elevated liver enzymes, sepsis. |
| 24 | 5 d | - | Microcephaly, cerebral calcifications (irregular and punctate), thrombocytopenia |
| 25 | 5 d | + | AWGA, hepatosplenomegaly, sepsis, jaundice. |
| 26 | 3 m | - | Chorioretinitis |
| 27 | 5 d | - | SGA, hepatosplenomegaly, petechiae, anaemia, cholestasis |
| 28 | 5 d | + | SGA, purpura, cerebral calcifications, thrombocytopenia, splenomegaly, elevated liver enzymes |
| 30 | 5 d | + | Hepatosplenomegaly, purpura |
| 31 | 5 m | - | RNPT, AWGA, seizures, maturational delay, palsy at age one year |
| Perinatal | |||
| 39 | 40 d | - | SGA, petechiae, hepatomegaly, respiratory problems. |
| 41 | 5 m | + | HIV+, cerebral calcifications, hepatosplenomegaly, anaemia |
| 47 | 34 d | + | Neonatal jaundice |
| 50 | 8 m | - | SGA, Hepatosplenomegaly, elevated liver enzymes, anaemia, jaundice at age 2 months |
| Congenital or Perinatal | |||
| 34, 37, 48 | 3 m, 8 m, 7 m | -, -, S/s | Hepatosplenomegaly, HIV+ |
| 35 | 4 m | + | Jaundice, biliary atresia |
| 36 | 63 d | + | Anaemia, hepatosplenomegaly, malnutrition, hyperbilirubinemia |
| 38, 43 | 4 m, 3 m | -, - | Petechiae, hyperbilirubinemia, splenomegaly |
| 40 | 40 d | - | Ascitis, renal problems, elevated liver enzymes |
| 42 | 42 d | S/s | SGA |
| 44 | 3 m | + | Premature, scanty maternal contact |
| 45 | 24 m | - | Malnutrition, pancytopenia. |
| 46 | 12 m | + | Aplastic crisis |
| 49 | 4 m | + | SGA, hepatosplenomegaly, jaundice, anaemia, petechiae. |
| 51 | 2 m | + | Sepsis, cyanosis, vomiting |
| 52 | 1 m | S/s | Petechiae, jaundice, anaemia, hepatosplenomegaly |
| 53 | 5 m | + | Mental retardation, anaemia |
| 54 | 2 m | - | RNPT, SGA, IUGR, anaemia, microcephaly, tricuspid valve insufficiency |
| 55 | 3 m | - | SGA, rash, fever spikes |
| 56, 58 | 5 m, 33 d | -, - | SGA, respiratory problems. |
| 57 | 34 d | + | IUGR, sepsis, hepatomegaly, oesophageal atresia, elevated liver enzymes |
| 59 | 26 d | - | SGA, HIV+ mother |
| 60 | 38 d | + | IUGR, microcephaly, jaundice |
| 61 | 6 m | - | Normal at birth, neutropenia |
IUGR, intrauterine growth retardation; SGA, small for gestational age; AWGA, adequate weight for gestational age. S/s, sera not collected