Table 4.

Definition of QOL in 46 randomized controlled trials reporting on QOL

	Number of trials
	Before 1993		1994–1998		1999–2003
	English Reports	Japanese Reports	English Reports	Japanese Reports	English Reports	Japanese Reports	Total
Investigators' definition of QOL	0 (0.0)	1 (25.0)	1 (12.5)	1 (16.7)	3 (14.3)	0 (0.0)	6 (13.0)
General definition of QOL	0 (0.0)	0 (0.0)	1 (12.5)	2 (33.3)	4 (19.0)	2 (50.0)	9 (19.6)
No definition	3 (100.0)	3 (75.0)	6 (75.0)	3 (50.0)	14 (66.7)	2 (50.0)	31 (67.4)
Total	3 (100.0)	4 (100.0)	8 (100.0)	6 (100.0)	21 (100.0)	4 (100.0)	46 (100.0)