Figure 4.

Apparent evolution of the 5′-deoxyadenosyl radical concentration modelled from the best-fit parameters for the 3-step model fitting in Figure 3. Transients are for: A) EA versus EAL, B) [D₄]EA versus [D₂]EAL, C) [D₄]EA versus EAL, and D) EA versus [D₂]EAL. In C and D the black transients are convolutions of the contributions from the initial H or D abstraction (red) and the “scrambled” partially deuterated 5′-deoxyadenosyl radical (blue). The vertical dotted line indicates the stopped-flow dead-time of about 1.5 ms.