Table 2.
•OH-elimination abilities and reducing abilities of ingredients of hangeshashinto
| Ingredient | Crude drug | M.W. | Reducing ability | IC50 of •OH elimination |
|---|---|---|---|---|
| k2nd (min−1M−1) | (mM) | |||
| acteoside | ogon | 624.6 | 0.203 | 5.32 |
| glycyrrhizin | kanzo | 822.9 | n.d. | 0.53 |
| glycyrrhetin | kanzo | 470.7 | n.d. | 6.63 |
| cyclic AMP | taiso | 329.2 | n.d. | 6.64 |
| ginsenoside Rg1 | ninjin | 801.2 | n.d. | 3.68 |
| ginsenoside Rb1 | ninjin | 1109.3 | n.d. | 42.61 |
| berberine chloride | oren | 371.8 | 0.455 | 6.17 |
| DMSO | ----- | 78.1 | n.d. | 6.9a |
| SDS | ----- | 288.7 | n.d. | 46.0a |
M.W. = molecular weight, n.d. = not detected. aValues are referenced from Ueno et al. [23].