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Major components of POH metabolism in mammals. POH, either derived from limonene via hydroxylation by P450 liver enzymes, or administered directly into the patient or other mammal, undergoes stepwise oxidation to its metabolic end products, followed by glucuronidation by UDP-glucuronyltransferase and subsequent excretion. (Shown are the (篓C)-(S)-enantiomers of the stereoisomeric molecules).
