Figure 2.
Representative MRIs of POH-treated patients. (A) MRIs of patient with astrocytoma grade II under treatment with four times daily intranasal POH at 66.7 mg/dose (266.8 mg/day). Note persistent tumor size in initial MRI (a), and after 3 years (b) of continuous treatment. (B) MRIs of patient with recurrent glioblastoma multiforme under treatment with same intranasal POH schedule (66.7 mg qid). Note mild reduction of tumor size from initial MRI (a) to 2 years (b) and 4 years (c) of daily treatment. (C) MRIs of patient with recurrent glioblastoma multiforme under treatment with same intranasal POH schedule (66.7 mg qid) in combination with temozolomide. Note mild reduction of tumor size from initial MRI (a) to 2 years (b) and 3 years (c) of daily POH treatment.